ZNF224 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ZNF224 antibody detected the ZNF224 protein (arrow).
ZNF224; BMZF2; KOX22; ZNF233; ZNF255; ZNF27; Zinc finger protein 224; Bone marrow zinc finger 2; Zinc finger protein 233; Zinc finger protein 255; Zinc finger protein 27; Zinc finger protein KOX22
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
BMZF2 KOX22 ZNF233 ZNF255 ZNF27
Alternative Names
ZNF224 BMZF2 KOX22 ZNF233 ZNF255 ZNF27 Zinc finger protein 224 Bone marrow zinc finger 2 Zinc finger protein 233 Zinc finger protein 255 Zinc finger protein 27 Zinc finger protein KOX22
Molecular Weight(MW)
82280 Da
Function
May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells
Tissue Specificity
Ubiquitous. Mainly expressed in fetal tissues.
Cellular Localization
Nucleus. Note=Co-localizes with DEPDC1A at the nucleus
ZNF224 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ZNF224 antibody detected the ZNF224 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.