Application
Western blot analysis of ZRANB1 Antibody (C-term) in K562 cell line lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.Application
Western blot analysis of ZRANB1 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.Application
ZRANB1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZRANB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ZRANB1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ZRANB1; TRABID; Ubiquitin thioesterase ZRANB1; TRAF-binding domain-containing protein; Zinc finger Ran-binding domain-containing protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TRABID |
|---|---|
| Alternative Names | ZRANB1 TRABID Ubiquitin thioesterase ZRANB1 TRAF-binding domain-containing protein Zinc finger Ran-binding domain-containing protein 1 |
| Molecular Weight(MW) | 80967 Da |
| Function | Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'- linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm |
| Entrez Gene | 54764 |
|---|
Application
Western blot analysis of ZRANB1 Antibody (C-term) in K562 cell line lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.
Application
Western blot analysis of ZRANB1 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.
Application
ZRANB1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZRANB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
