Application
ZW10 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the ZW10 antibody detected the ZW10 protein (arrow).| Product Name | ZW10 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ZW10; Centromere/kinetochore protein zw10 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ZW10 Centromere/kinetochore protein zw10 homolog |
|---|---|
| Molecular Weight(MW) | 88829 Da |
| Function | Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Chromosome, centromere, kinetochore Cytoplasm, cytoskeleton, spindle. Note=Dynamic pattern of localization during the cell cycle. In most cells at interphase, present diffusely in the cytoplasm. In prometaphase, associated with the kinetochore. At metaphase, detected both at the kinetochores and, most prominently, at the spindle, particularly at the spindle poles. In very early anaphase, detected on segregating kinetochores. In late anaphase and telophase, accumulates at the spindle midzone |
| Entrez Gene | 9183 |
|---|---|
| Nucleotide Accession | NP_004715.1 |
Application
ZW10 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the ZW10 antibody detected the ZW10 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
