Application
Western blot analysis of ABCC11 Antibody (N-term) in WiDr cell line lysates (35ug/lane). ABCC11 (arrow) was detected using the purified Pab.Application
ABCC11 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC11 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ABCC11 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABCC11; MRP8; ATP-binding cassette sub-family C member 11; Multidrug resistance-associated protein 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MRP8 |
|---|---|
| Alternative Names | ABCC11 MRP8 ATP-binding cassette sub-family C member 11 Multidrug resistance-associated protein 8 |
| Molecular Weight(MW) | 154301 Da |
| Function | Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax |
| Tissue Specificity | Expressed in many tissues. Not expressed in kidney, spleen and colon. Highly expressed in breast cancer Expressed at moderate levels in normal breast and testis and at very low levels in liver, brain and placenta |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 85320 |
|---|
Application
Western blot analysis of ABCC11 Antibody (N-term) in WiDr cell line lysates (35ug/lane). ABCC11 (arrow) was detected using the purified Pab.
Application
ABCC11 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC11 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
