ABCG1, ABC8, WHT1, ATP-binding cassette sub-family G member 1, ATP-binding cassette transporter 8;White protein homolog
Key Feature
Clonality
Monoclonal
Clone Number
EP1366Y
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:2000~10000 IHC
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
ABC8 WHT1
Alternative Names
ABCG1 ABC8 WHT1 ATP-binding cassette sub-family G member 1 ATP-binding cassette transporter 8 White protein homolog
Molecular Weight(MW)
75592 Da
Function
Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages
Tissue Specificity
Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease
Cellular Localization
Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes