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ABCG1 Antibody (N-term)
Catalog Number:OM225613
OM225613
Discount Price
OM225613-100ul
1~2 Week
100ul
OM225613-50ul
50ul
OM225613-20ul
20ul
1~2 Week
Product Profile
Product Name ABCG1 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias ABCG1; ABC8; WHT1; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFCIHCIF
WB:1:50~100 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ABC8
WHT1
Alternative Names ABCG1
ABC8
WHT1
ATP-binding cassette sub-family G member 1
ATP-binding cassette transporter 8
White protein homolog
Molecular Weight(MW) 75592 Da
Function Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages
Tissue Specificity Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease
Cellular Localization Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes
Database Links
Entrez Gene 9619
Application

Application

Western blot analysis of ABCG1 antibody (N-term) (Cat.# AP6529a) in mouse spleen tissue lysates (35ug/lane). ABCG1 (arrow) was detected using the purified Pab.

Application

ABCG1 Antibody (N-term) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

ABCG1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCG1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

Confocal immunofluorescent analysis of ABCG1 Antibody (N-term)(Cat#AP6529a) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application Notes WB:1:50~100 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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