Application
ABRA Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the ABRA antibody detected the ABRA protein (arrow).Application
ABRA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABRA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ABRA Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABRA; Actin-binding Rho-activating protein; Striated muscle activator of Rho-dependent signaling |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ABRA Actin-binding Rho-activating protein Striated muscle activator of Rho-dependent signaling |
|---|---|
| Molecular Weight(MW) | 43117 Da |
| Function | Acts as an activator of serum response factor (SRF)- dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity) |
| Tissue Specificity | This ABRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-312 amino acids from the C-terminal region of human ABRA. |
| Cellular Localization | Cytoplasm, myofibril, sarcomere (By similarity). Cytoplasm, cytoskeleton (By similarity) Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines (By similarity) |
| Entrez Gene | 137735 |
|---|---|
| Nucleotide Accession | NP_631905.1 |
Application
ABRA Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the ABRA antibody detected the ABRA protein (arrow).
Application
ABRA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABRA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
