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ACE Antibody

Catalog Number:OM225684
OM225684
Discount Price
OM225684-100ul
1~2 Week
100ul
OM225684-50ul
50ul
OM225684-20ul
20ul
1~2 Week
Product Profile
Product Name ACE Antibody
Antibody Type Primary Antibodies
Antigen Alias ACE, DCP, DCP1, Angiotensin-converting enzyme, soluble form, Dipeptidyl carboxypeptidase I;Kininase II
Key Feature
Clonality Monoclonal
Clone Number EPR2757
Host Species Rabbit
Tested Applications WBIHC
WB:1:1000~10000 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms DCP
DCP1
Alternative Names ACE
DCP
DCP1
Angiotensin-converting enzyme
soluble form
Dipeptidyl carboxypeptidase I
Kininase II
Molecular Weight(MW) 149715 Da
Function Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety
Tissue Specificity Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis
Cellular Localization Angiotensin-converting enzyme, soluble form: Secreted
Database Links
Entrez Gene 1636
Application

Application

A. Western blot analysis on (A) fetal kidney, (B) fetal heart and (C) fetal lung lysates using anti-ACE (angiotensin converting enzyme) RabMAb (Cat. #AJ1009a), dilution 1:1000.

Application

B.Immunohistochemical analysis of paraffin-embedded human kidney using anti-ACE (angiotensin converting enzyme) RabMAb (Cat. #AJ1009a).

Application

C.Immunohistochemical analysis of paraffin-embedded spleen using anti-ACE (angiotensin converting enzyme) RabMAb Note positive staining of endothelial cells (Cat. #AJ1009a).
Application Notes WB:1:1000~10000 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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