Application
ACER1 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ACER1 antibody detected the ACER1 protein (arrow).| Product Name | ACER1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACER1; ASAH3; Alkaline ceramidase 1; Acylsphingosine deacylase 3; N-acylsphingosine amidohydrolase 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ASAH3 |
|---|---|
| Alternative Names | ACER1 ASAH3 Alkaline ceramidase 1 Acylsphingosine deacylase 3 N-acylsphingosine amidohydrolase 3 |
| Molecular Weight(MW) | 31095 Da |
| Function | Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo- phytosphingosine or D-erythro-dihydrosphingosine as a backbone May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity) |
| Tissue Specificity | Mainly expressed in epidermis. |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 125981 |
|---|---|
| Nucleotide Accession | NP_597999.1 |
Application
ACER1 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ACER1 antibody detected the ACER1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
