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ADAM19 Antibody (Center)

Catalog Number:OM225865
OM225865
Discount Price
OM225865-100ul
1~2 Week
100ul
OM225865-50ul
50ul
OM225865-20ul
20ul
1~2 Week
Product Profile
Product Name ADAM19 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias ADAM19; MLTNB; Disintegrin and metalloproteinase domain-containing protein 19; Meltrin-beta; Metalloprotease and disintegrin dendritic antigen marker
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:50~100 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms MLTNB
Alternative Names ADAM19
MLTNB
Disintegrin and metalloproteinase domain-containing protein 19
Meltrin-beta
Metalloprotease and disintegrin dendritic antigen marker
Molecular Weight(MW) 104997 Da
Function Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity)
Tissue Specificity Expressed in many normal organ tissues and several cancer cell lines
Cellular Localization Membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 8728
Application

Application

Western blot analysis of ADAM19 Antibody (Center) in WiDr cell line lysates (35ug/lane). ADAM19 (arrow) was detected using the purified Pab.

Application

ADAM19 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ADAM19 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

ADAM19 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:50~100 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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