Application
Western blot analysis of anti-ADAMTS4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ADAMTS4 (arrow) was detected using the purified Pab.| Product Name | ADAMTS4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADAMTS4; KIAA0688; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADMP-1; Aggrecanase-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0688 |
|---|---|
| Alternative Names | ADAMTS4 KIAA0688 A disintegrin and metalloproteinase with thrombospondin motifs 4 ADMP-1 Aggrecanase-1 |
| Molecular Weight(MW) | 90197 Da |
| Function | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site |
| Tissue Specificity | Expressed in brain, lung and heart. Expressed at very low level in placenta and skeletal muscles |
| Cellular Localization | Secreted, extracellular space, extracellular matrix (By similarity) |
| Entrez Gene | 9507 |
|---|
Application
Western blot analysis of anti-ADAMTS4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ADAMTS4 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
