Application
ADI1 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ADI1 antibody detected the ADI1 protein (arrow).| Product Name | ADI1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADI1; MTCBP1; 1, 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; Submergence-induced protein-like factor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MTCBP1 |
|---|---|
| Alternative Names | ADI1 MTCBP1 1 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase Acireductone dioxygenase (Fe(2+)-requiring) Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 Submergence-induced protein-like factor |
| Molecular Weight(MW) | 21498 Da |
| Function | Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line |
| Tissue Specificity | Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney |
| Cellular Localization | Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14 |
| Entrez Gene | 55256 |
|---|---|
| Nucleotide Accession | NP_060739.2 |
Application
ADI1 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ADI1 antibody detected the ADI1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
