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Adiponectin Antibody

Catalog Number:OM225929
OM225929
Discount Price
OM225929-100ul
1~2 Week
100ul
OM225929-50ul
50ul
OM225929-20ul
20ul
1~2 Week
Product Profile
Product Name Adiponectin Antibody
Antibody Type Primary Antibodies
Antigen Alias ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adiponectin, Gelatin-binding protein
Key Feature
Clonality Monoclonal
Clone Number EPR3217
Host Species Rabbit
Tested Applications WB
WB:1:2000~20000
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ACDC
ACRP30
APM1
GBP28
Alternative Names ADIPOQ
ACDC
ACRP30
APM1
GBP28
Adiponectin
Gelatin-binding protein
Molecular Weight(MW) 26414 Da
Function Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW
Tissue Specificity Synthesized exclusively by adipocytes and secreted into plasma
Cellular Localization Secreted.
Database Links
Entrez Gene 9370
Application

Application

A.Western blot analysis on (A) fetal fat and (B) human plasma lysates using anti-Adiponectin RabMAb (Cat. #AJ1017a), dilution 1:5000.
Application Notes WB:1:2000~20000
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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