A.Western blot analysis on (A) human fat and (B) human placenta and (C) human plasma lysates using anti-Adiponectin RabMAb (Cat. #AJ1017b), dilution 1:10,000.
ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adiponectin, Gelatin-binding protein
Key Feature
Clonality
Monoclonal
Clone Number
EPR3218
Host Species
Rabbit
Tested Applications
WB
WB:1:5000~10000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
ACDC ACRP30 APM1 GBP28
Alternative Names
ADIPOQ ACDC ACRP30 APM1 GBP28 Adiponectin Gelatin-binding protein
Molecular Weight(MW)
26414 Da
Function
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW
Tissue Specificity
Synthesized exclusively by adipocytes and secreted into plasma
A.Western blot analysis on (A) human fat and (B) human placenta and (C) human plasma lysates using anti-Adiponectin RabMAb (Cat. #AJ1017b), dilution 1:10,000.
Application Notes
WB:1:5000~10000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.