Application
Western blot analysis of ADM Antibody (Center) in mouse lung tissue lysates (35ug/lane).ADM (arrow) was detected using the purified Pab.Application
ADM Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | ADM Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADM; AM; Adrenomedullin; Proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AM |
|---|---|
| Alternative Names | ADM AM Adrenomedullin Proadrenomedullin N-20 terminal peptide ProAM N-terminal 20 peptide |
| Molecular Weight(MW) | 20420 Da |
| Function | AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels |
| Tissue Specificity | Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues |
| Cellular Localization | Secreted. |
| Entrez Gene | 133 |
|---|
Application
Western blot analysis of ADM Antibody (Center) in mouse lung tissue lysates (35ug/lane).ADM (arrow) was detected using the purified Pab.
Application
ADM Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
