Application
Western blot analysis of ADPRHL2 Antibody (N-term) in Hela cell line lysates (35ug/lane). ADPRHL2 (arrow) was detected using the purified Pab.Application
ADPRHL2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | ADPRHL2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADPRHL2; ARH3; Poly(ADP-ribose) glycohydrolase ARH3; ADP-ribosylhydrolase 3; [Protein ADP-ribosylarginine] hydrolase-like protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARH3 |
|---|---|
| Alternative Names | ADPRHL2 ARH3 Poly(ADP-ribose) glycohydrolase ARH3 ADP-ribosylhydrolase 3 [Protein ADP-ribosylarginine] hydrolase-like protein 2 |
| Molecular Weight(MW) | 38947 Da |
| Function | Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP- ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. Mitochondrion matrix. Nucleus. |
| Entrez Gene | 54936 |
|---|
Application
Western blot analysis of ADPRHL2 Antibody (N-term) in Hela cell line lysates (35ug/lane). ADPRHL2 (arrow) was detected using the purified Pab.
Application
ADPRHL2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
