Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine
Tissue Specificity
This ADRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371~401 amino acids surrounding T384 of human BAR2.
Cellular Localization
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane
Western blot analysis of anti-ADRB2 Antibody (T384) in SK-BR-3 cell line lysates (35ug/lane). ADRB2 (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.