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ADRB2 Antibody (S364)

Catalog Number:OM225971
OM225971
Discount Price
OM225971-100ul
1~2 Week
100ul
OM225971-50ul
50ul
OM225971-20ul
20ul
1~2 Week
Product Profile
Product Name ADRB2 Antibody (S364)
Antibody Type Primary Antibodies
Antigen Alias ADRB2; ADRB2R; B2AR; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:50~100 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ADRB2R
B2AR
Alternative Names ADRB2
ADRB2R
B2AR
Beta-2 adrenergic receptor
Beta-2 adrenoreceptor
Molecular Weight(MW) 46459 Da
Function Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine
Tissue Specificity This ADRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352~381 amino acids surrounding S364 of human BAR2.
Cellular Localization Cell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane
Database Links
Entrez Gene 154
Application

Application

Western blot analysis of anti-ADRB2 Antibody (S364) in NCI-H460 cell line lysates (35ug/lane). ADRB2 (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human brain reacted with ADRB2 Antibody (S364), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

Flow cytometric analysis of NCI-H292 cells using ADRB2 Antibody (S364)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:50~100 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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