Application
A. Western blot analysis on U937 cell lysate using anti- Beta-ARK1 (GRK2) RabMAb (Cat. #AJ1090a). dilution 1:500.Application
B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-Beta-ARK1 (GRK2) RabMAb (Cat. #AJ1090a).| Product Name | ADRBK1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADRBK1, BARK, BARK1, GRK2, Beta-adrenergic receptor kinase 1, G-protein coupled receptor kinase 2 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | Y137 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BARK BARK1 GRK2 |
|---|---|
| Alternative Names | ADRBK1 BARK BARK1 GRK2 Beta-adrenergic receptor kinase 1 G-protein coupled receptor kinase 2 |
| Molecular Weight(MW) | 79574 Da |
| Function | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner |
| Tissue Specificity | Expressed in peripheral blood leukocytes. |
| Entrez Gene | 156 |
|---|
Application
A. Western blot analysis on U937 cell lysate using anti- Beta-ARK1 (GRK2) RabMAb (Cat. #AJ1090a). dilution 1:500.
Application
B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-Beta-ARK1 (GRK2) RabMAb (Cat. #AJ1090a).| Application Notes | WB:1:500~1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
