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ADRBK1 Antibody (N-term)

Catalog Number:OM225973
OM225973
Discount Price
OM225973-100ul
1~2 Week
100ul
OM225973-50ul
50ul
OM225973-20ul
20ul
1~2 Week
Product Profile
Product Name ADRBK1 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias ADRBK1; BARK; BARK1; GRK2; Beta-adrenergic receptor kinase 1; G-protein coupled receptor kinase 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:50~100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms BARK
BARK1
GRK2
Alternative Names ADRBK1
BARK
BARK1
GRK2
Beta-adrenergic receptor kinase 1
G-protein coupled receptor kinase 2
Molecular Weight(MW) 79574 Da
Function Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner
Tissue Specificity Expressed in peripheral blood leukocytes.
Database Links
Entrez Gene 156
Application

Application

Western blot analysis of ADRBK1 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). ADRBK1 (arrow) was detected using the purified Pab.

Application

Western blot analysis of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2) (Origene Technologies).
Application Notes WB:1:50~100
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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