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AGR2 Antibody

Catalog Number:OM226037
OM226037
Discount Price
OM226037-100ul
1~2 Week
100ul
OM226037-50ul
50ul
OM226037-20ul
20ul
1~2 Week
Product Profile
Product Name AGR2 Antibody
Antibody Type Primary Antibodies
Key Feature
Clonality Monoclonal
Clone Number EPR3279
Host Species Rabbit
Tested Applications WB
WB:1:500~1000
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms AG2
Alternative Names AGR2
AG2
Anterior gradient protein 2 homolog
Secreted cement gland protein XAG-2 homolog
HPC8
Molecular Weight(MW) 19979 Da
Function Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth
Tissue Specificity Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines
Cellular Localization Secreted. Endoplasmic reticulum (By similarity)
Database Links
Entrez Gene 10551
Application

Application

A.Western blot analysis on (A) HT-29 and (B) MCF-7 cell lysates using anti-AGR2 RabMAb (Cat. #AJ1020a), dilution 1:2000.

Application

B.High expression of AGR2 protein in breast ductal infiltrating carcinoma tissue detected by anti-AGR2 RabMAB (Cat. #AJ1020a).

Application

C.Weak expression of AGR2 protein in normal breast tissue detected by anti-AGR2 RabMAB (Cat. #AJ1020a).
Application Notes WB:1:500~1000
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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