Application
Western blot analysis of AIFM2 antibody (Center) in NCI-H460 cell line lysates (35ug/lane). AIFM2 (arrow) was detected using the purified Pab .| Product Name | AIFM2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AMID, PRG3 |
|---|---|
| Alternative Names | AIFM2 AMID PRG3 Apoptosis-inducing factor 2 Apoptosis-inducing factor homologous mitochondrion-associated inducer of death Apoptosis-inducing factor-like mitochondrion-associated inducer of death p53-responsive gene 3 protein |
| Molecular Weight(MW) | 40527 Da |
| Function | Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest |
| Tissue Specificity | Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells |
| Cellular Localization | Cytoplasm. Mitochondrion outer membrane. |
| Entrez Gene | 84883 |
|---|
Application
Western blot analysis of AIFM2 antibody (Center) in NCI-H460 cell line lysates (35ug/lane). AIFM2 (arrow) was detected using the purified Pab .| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
