Application
AKAP5 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the AKAP5 antibody detected the AKAP5 protein (arrow).| Product Name | AKAP5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AKAP79 |
|---|---|
| Alternative Names | AKAP5 AKAP79 A-kinase anchor protein 5 A-kinase anchor protein 79 kDa H21 cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein |
| Molecular Weight(MW) | 47088 Da |
| Function | May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade |
| Tissue Specificity | Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary |
| Cellular Localization | Membrane; Lipid-anchor. Note=Associates with lipid rafts |
| Entrez Gene | 9495 |
|---|---|
| Nucleotide Accession | NP_004848.3 |
Application
AKAP5 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the AKAP5 antibody detected the AKAP5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
