Application
AKR1C2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the AKR1C2 antibody detected the AKR1C2 protein (arrow).Application
AKR1C2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | AKR1C2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DDH2 |
|---|---|
| Alternative Names | AKR1C2 DDH2 Aldo-keto reductase family 1 member C2 3-alpha-HSD3 Chlordecone reductase homolog HAKRD Dihydrodiol dehydrogenase 2 Dihydrodiol dehydrogenase/bile acid-binding protein Trans-1 2-dihydrobenzene-1 2-diol dehydrogenase Type III 3-alpha-h |
| Molecular Weight(MW) | 36735 Da |
| Function | Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol) Has a high bile-binding ability |
| Tissue Specificity | Expressed in fetal testes. Expressed in fetal and adult adrenal glands |
| Cellular Localization | Cytoplasm (Potential). |
| Entrez Gene | 1646 |
|---|---|
| Nucleotide Accession | NP_995317.1 |
Application
AKR1C2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the AKR1C2 antibody detected the AKR1C2 protein (arrow).
Application
AKR1C2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
