Application
AKR1D1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AKR1D1 antibody detected the AKR1D1 protein (arrow).| Product Name | AKR1D1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SRD5B1 |
|---|---|
| Alternative Names | AKR1D1 SRD5B1 3-oxo-5-beta-steroid 4-dehydrogenase Aldo-keto reductase family 1 member D1 Delta(4)-3-ketosteroid 5-beta-reductase Delta(4)-3-oxosteroid 5-beta-reductase |
| Molecular Weight(MW) | 37377 Da |
| Function | Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7- alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4- cholesten-3-one can also act as substrates |
| Tissue Specificity | Highly expressed in liver. Expressed in testis and weakly in colon |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 6718 |
|---|---|
| Nucleotide Accession | NP_005980.1 |
Application
AKR1D1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AKR1D1 antibody detected the AKR1D1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
