Application
ALS2CL Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ALS2CL antibody detected the ALS2CL protein (arrow).| Product Name | ALS2CL Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ALS2CL ALS2 C-terminal-like protein |
|---|---|
| Molecular Weight(MW) | 107748 Da |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics |
| Tissue Specificity | Expressed in heart and kidney. |
| Cellular Localization | Cytoplasm. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells |
| Entrez Gene | 259173 |
|---|---|
| Nucleotide Accession | NP_001177636.1 |
Application
ALS2CL Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ALS2CL antibody detected the ALS2CL protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
