Western blot analysis of ALS2CR2 (arrow) using ALS2CR2 Antibody (C-term L289) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALS2CR2 gene (Lane 2) (Origene Technologies).
STRADB ALS2CR2 ILPIP STE20-related kinase adapter protein beta Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein CALS-21 ILP-interacting protein Pseudokinase ALS2CR2
Molecular Weight(MW)
47026 Da
Function
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity)
Tissue Specificity
Highly expressed in heart, skeletal muscle, testis, liver and colon
Western blot analysis of ALS2CR2 (arrow) using ALS2CR2 Antibody (C-term L289) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALS2CR2 gene (Lane 2) (Origene Technologies).
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.