AMICA1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AMICA1 antibody detected the AMICA1 protein (arrow).
AMICA1; JAML; Junctional adhesion molecule-like; Adhesion molecule interacting with CXADR antigen 1; Dendritic cell-specific protein CREA7-1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
JAML
Alternative Names
AMICA1 JAML Junctional adhesion molecule-like Adhesion molecule interacting with CXADR antigen 1 Dendritic cell-specific protein CREA7-1
Molecular Weight(MW)
44339 Da
Function
May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells
Tissue Specificity
Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus
Cellular Localization
Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN
AMICA1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AMICA1 antibody detected the AMICA1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.