Application
Western blot analysis of AMOTL2 Antibody (Center) in A375 cell line lysates (35ug/lane). AMOTL2 (arrow) was detected using the purified Pab.Application
Western blot analysis of AMOTL2 Antibody (Center) in mouse liver tissue lysates (35ug/lane). AMOTL2 (arrow) was detected using the purified Pab.| Product Name | AMOTL2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AMOTL2; KIAA0989; Angiomotin-like protein 2; Leman coiled-coil protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0989 |
|---|---|
| Alternative Names | AMOTL2 KIAA0989 Angiomotin-like protein 2 Leman coiled-coil protein |
| Molecular Weight(MW) | 85764 Da |
| Function | Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC |
| Tissue Specificity | This AMOTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132~161 amino acids from the Center region of human AMOTL2. |
| Cellular Localization | Recycling endosome (By similarity). |
| Entrez Gene | 51421 |
|---|
Application
Western blot analysis of AMOTL2 Antibody (Center) in A375 cell line lysates (35ug/lane). AMOTL2 (arrow) was detected using the purified Pab.
Application
Western blot analysis of AMOTL2 Antibody (Center) in mouse liver tissue lysates (35ug/lane). AMOTL2 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
