Application
ANG Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ANG antibody detected the ANG protein (arrow).| Product Name | ANG Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANG; RNASE5; Angiogenin; Ribonuclease 5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RNASE5 |
|---|---|
| Alternative Names | ANG RNASE5 Angiogenin Ribonuclease 5 |
| Molecular Weight(MW) | 16550 Da |
| Function | May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo |
| Tissue Specificity | Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons |
| Cellular Localization | Secreted. |
Application
ANG Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ANG antibody detected the ANG protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
