Application
ANO6 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ANO6 antibody detected the ANO6 protein (arrow).| Product Name | ANO6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANO6; TMEM16F; Anoctamin-6; Transmembrane protein 16F |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TMEM16F |
|---|---|
| Alternative Names | ANO6 TMEM16F Anoctamin-6 Transmembrane protein 16F |
| Molecular Weight(MW) | 106165 Da |
| Function | Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes |
| Tissue Specificity | Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Note=Shows an intracellular localization according to PubMed:22075693 |
| Entrez Gene | 196527 |
|---|---|
| Nucleotide Accession | NP_001020527.2 |
Application
ANO6 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ANO6 antibody detected the ANO6 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
