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Apobec1 Antibody (N-term)

Catalog Number:OM226678
OM226678
Discount Price
OM226678-100ul
1~2 Week
100ul
OM226678-50ul
50ul
OM226678-20ul
20ul
1~2 Week
Product Profile
Product Name Apobec1 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias APOBEC1; C->U-editing enzyme APOBEC-1; Apolipoprotein B mRNA-editing enzyme 1; HEPR
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names APOBEC1
C->U-editing enzyme APOBEC-1
Apolipoprotein B mRNA-editing enzyme 1
HEPR
Molecular Weight(MW) 28192 Da
Function Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation
Tissue Specificity Expressed exclusively in the small intestine.
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 339
Nucleotide Accession NP_001635
Application

Application

The anti-Apobec1 N-term Pab is used in Western blot to detect Apobec in mouse small intestine tissue lysate.

Application

Western blot analysis of anti-Apobec1 Antibody (N-term) in 293 cell line lysates (35ug/lane). Apobec1(arrow) was detected using the purified Pab (1:60dilution).

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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