Application
A. Western blot analysis on human serum using anti-Apo E RabMAb. (Cat. #AJ1053a).Application
B. Immunohistochemical analysis of paraffin-embedded human fetal liver using anti-Apo E RabMAb (Cat. #AJ1053a).| Product Name | Apolipoprotein E Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APOE, Apolipoprotein E |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1373Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | APOE Apolipoprotein E |
|---|---|
| Molecular Weight(MW) | 36154 Da |
| Function | Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues |
| Tissue Specificity | Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle |
| Cellular Localization | Secreted. |
| Entrez Gene | 348 |
|---|
Application
A. Western blot analysis on human serum using anti-Apo E RabMAb. (Cat. #AJ1053a).
Application
B. Immunohistochemical analysis of paraffin-embedded human fetal liver using anti-Apo E RabMAb (Cat. #AJ1053a).| Application Notes | WB:1:500~1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
