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APOO Antibody (N-term )

Catalog Number:OM226725
OM226725
Discount Price
OM226725-100ul
1~2 Week
100ul
OM226725-50ul
50ul
OM226725-20ul
20ul
1~2 Week
Product Profile
Product Name APOO Antibody (N-term )
Antibody Type Primary Antibodies
Antigen Alias APOO; FAM121B; Apolipoprotein O; Protein FAM121B
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms FAM121B
Alternative Names APOO
FAM121B
Apolipoprotein O
Protein FAM121B
Molecular Weight(MW) 22285 Da
Function Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation
Tissue Specificity Expressed in all tissues examined. Up- regulated in diabetic heart
Cellular Localization Membrane; Single-pass membrane protein (Potential). Secreted
Database Links
Entrez Gene 79135
Nucleotide Accession NP_077027.1
Application

Application

APOO Antibody (N-term ) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APOO antibody detected the APOO protein (arrow).

Application

APOO Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of APOO Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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