Application
A. Western blot analysis on fetal liver lysate using anti-Apo A1 RabMAb (Cat. #AJ1056a).Application
B. Immunohistochemical staining of paraffin-embedded human liver using anti-Apo-A1RabMAb (Cat. #AJ1056a).Application
C. Immunofluorescent staining of HEPG2 cells using anti-Apo- A1 RabMAb (Cat. #AJ1056a).| Product Name | Apolipoprotein-A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APOA1, Apolipoprotein A-I(1-242) |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1368Y |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | APOA1 Apolipoprotein A-I(1-242) |
|---|---|
| Molecular Weight(MW) | 30778 Da |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility |
| Tissue Specificity | Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease |
| Cellular Localization | Secreted. |
| Entrez Gene | 335 |
|---|
Application
A. Western blot analysis on fetal liver lysate using anti-Apo A1 RabMAb (Cat. #AJ1056a).
Application
B. Immunohistochemical staining of paraffin-embedded human liver using anti-Apo-A1RabMAb (Cat. #AJ1056a).
Application
C. Immunofluorescent staining of HEPG2 cells using anti-Apo- A1 RabMAb (Cat. #AJ1056a).| Application Notes | WB:1:500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
