Application
Western blot analysis of APPL2 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in NCI-H292 cell line lysate. APPL2 Antibody (N-term) (arrow) was detected using the purified Pab (1:60/250 dilution).| Product Name | APPL2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APPL2; DIP13B; DCC-interacting protein 13-beta; Adapter protein containing PH domain, PTB domain and leucine zipper motif 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DIP13B |
|---|---|
| Alternative Names | APPL2 DIP13B DCC-interacting protein 13-beta Adapter protein containing PH domain PTB domain and leucine zipper motif 2 |
| Molecular Weight(MW) | 74493 Da |
| Function | Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction |
| Tissue Specificity | High levels in brain, heart, kidney and skeletal muscle |
| Cellular Localization | Early endosome membrane; Peripheral membrane protein. Nucleus. Note=Early endosomal membrane-bound and nuclear Translocated into the nucleus upon release from endosomal membranes following internalization of EGF |
| Entrez Gene | 55198 |
|---|---|
| Nucleotide Accession | NP_060641.2 |
Application
Western blot analysis of APPL2 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in NCI-H292 cell line lysate. APPL2 Antibody (N-term) (arrow) was detected using the purified Pab (1:60/250 dilution).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
