Application
AQP3 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the AQP3 antibody detected the AQP3 protein (arrow).Application
AQP3 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the AQP3 antibody detected the AQP3 protein (arrow).| Product Name | AQP3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AQP3; Aquaporin-3; Aquaglyceroporin-3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | AQP3 Aquaporin-3 Aquaglyceroporin-3 |
|---|---|
| Molecular Weight(MW) | 31544 Da |
| Function | Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity) |
| Tissue Specificity | Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein. Note=In collecting ducts of kidney |
| Entrez Gene | 360 |
|---|---|
| Nucleotide Accession | NP_004916.1 |
Application
AQP3 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the AQP3 antibody detected the AQP3 protein (arrow).
Application
AQP3 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the AQP3 antibody detected the AQP3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
