Application
AR Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AR antibody detected the AR protein (arrow).| Product Name | AR Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AR; DHTR; NR3C4; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DHTR NR3C4 |
|---|---|
| Alternative Names | AR DHTR NR3C4 Androgen receptor Dihydrotestosterone receptor Nuclear receptor subfamily 3 group C member 4 |
| Molecular Weight(MW) | 98989 Da |
| Function | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 |
| Tissue Specificity | Isoform 2 is mainly expressed in heart and skeletal muscle |
| Cellular Localization | Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1 |
| Entrez Gene | 367 |
|---|---|
| Nucleotide Accession | NP_001011645.1 NP_000035.2 |
Application
AR Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AR antibody detected the AR protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
