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Androgen receptor Antibody

Catalog Number:OM226453
OM226453
Discount Price
OM226453-100ul
1~2 Week
100ul
OM226453-50ul
50ul
1~2 Week
Product Profile
Product Name Androgen receptor Antibody
Antibody Type Primary Antibodies
Antigen Alias NR3C4; KD; AIS; SMAX1; HUMARA; AR
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 2H8
Host Species Mouse
Tested Applications WB
WB:1:500 - 2000.
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms DHTR
NR3C4
Alternative Names NR3C4
KD
AIS
SMAX1
HUMARA
AR
Molecular Weight(MW) 98989 Da
Function Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3
Tissue Specificity Isoform 2 is mainly expressed in heart and skeletal muscle
Cellular Localization Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1
Database Links
Entrez Gene 367
Nucleotide Accession NP_001011645.1
Application

Application

Figure 1: Western blot analysis using Androgen receptor mouse mAb against K562 (1), Jurkat (2) and LNCaP (3) cell lysate.

Application

Figure 2: Western blot analysis using Androgen receptor mouse mAb against human recombinant Androgen receptor.

Application

Figure 3: Western blot analysis using Androgen receptor mouse mAb against Androgen receptor (aa221-321)-hIgGFc transfected HEK293 cell lysate.
Application Notes WB:1:500 - 2000.
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified recombinant fragment of human AR expressed in E. Coli.
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