Application
ARC Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ARC antibody detected the ARC protein (arrow).| Product Name | ARC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARC; KIAA0278; Activity-regulated cytoskeleton-associated protein; ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0278 |
|---|---|
| Alternative Names | ARC KIAA0278 Activity-regulated cytoskeleton-associated protein ARC/ARG3.1 Activity-regulated gene 3.1 protein homolog |
| Molecular Weight(MW) | 45316 Da |
| Function | Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity) Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration |
| Tissue Specificity | This ARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-66 amino acids from the N-terminal region of human ARC. |
| Cellular Localization | Cytoplasm, cytoskeleton (By similarity). Endosome (By similarity). Cytoplasmic vesicle, secretory vesicle, acrosome (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell projection, dendrite (By similarity). Cell projection, dendritic spine (By similarity). Cell junction, synapse (By similarity) Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines Associated with the sperm tail (By similarity). Enriched on the plasma membrane |
| Entrez Gene | 23237 |
|---|---|
| Nucleotide Accession | NP_056008.1 |
Application
ARC Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ARC antibody detected the ARC protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
