Application
ARHGAP22 Antibody (C-term) western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ARHGAP22 antibody detected the ARHGAP22 protein (arrow).| Product Name | ARHGAP22 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARHGAP22; RHOGAP2; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RHOGAP2 |
|---|---|
| Alternative Names | ARHGAP22 RHOGAP2 Rho GTPase-activating protein 22 Rho-type GTPase-activating protein 22 |
| Molecular Weight(MW) | 76779 Da |
| Function | Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity) |
| Tissue Specificity | This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-633 amino acids from the C-terminal region of human ARHGAP22. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity) |
| Entrez Gene | 58504 |
|---|---|
| Nucleotide Accession | NP_067049.2 |
Application
ARHGAP22 Antibody (C-term) western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ARHGAP22 antibody detected the ARHGAP22 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
