Application
Western blot analysis of hARL7-E176 in CEM cell line lysates (35ug/lane). ARL7 (arrow) was detected using the purified Pab.| Product Name | ARL7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARL4C; ARL7; ADP-ribosylation factor-like protein 4C; ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARL7 |
|---|---|
| Alternative Names | ARL4C ARL7 ADP-ribosylation factor-like protein 4C ADP-ribosylation factor-like protein 7 ADP-ribosylation factor-like protein LAK |
| Molecular Weight(MW) | 21487 Da |
| Function | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP- bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process |
| Tissue Specificity | Expressed in several tumor cell lines (at protein level). Expressed in lung, brain, leukocytes and placenta |
| Cellular Localization | Cell projection, filopodium. Cell membrane. Cytoplasm |
Application
Western blot analysis of hARL7-E176 in CEM cell line lysates (35ug/lane). ARL7 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
