Application
ARNT Antibody (V528) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ARNT antibody detected the ARNT protein (arrow).| Product Name | ARNT Antibody (Center V528) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; Class E basic helix-loop-helix protein 2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHE2 |
|---|---|
| Alternative Names | ARNT BHLHE2 Aryl hydrocarbon receptor nuclear translocator Class E basic helix-loop-helix protein 2 Dioxin receptor nuclear translocator Hypoxia-inducible factor 1-beta |
| Molecular Weight(MW) | 86636 Da |
| Function | Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia |
| Tissue Specificity | This ARNT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 512-544 amino acids from the Central region of human ARNT. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 405 |
|---|---|
| Nucleotide Accession | NP_848514.1 NP_001659.1 |
Application
ARNT Antibody (V528) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ARNT antibody detected the ARNT protein (arrow).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
