Application
ASAP1 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ASAP1 antibody detected the ASAP1 protein (arrow).| Product Name | ASAP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ASAP1; DDEF1; KIAA1249; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; 130 kDa phosphatidylinositol 4, 5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; Developm |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DDEF1 KIAA1249 |
|---|---|
| Alternative Names | ASAP1 DDEF1 KIAA1249 Arf-GAP with SH3 domain ANK repeat and PH domain-containing protein 1 130 kDa phosphatidylinositol 4 5-bisphosphate-dependent ARF1 GTPase-activating protein ADP-ribosylation factor-directed GTPase-activating protein 1 Developm |
| Molecular Weight(MW) | 125498 Da |
| Function | Possesses phosphatidylinositol 4,5-bisphosphate- dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis |
| Tissue Specificity | This ASAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the Central region of human ASAP1. |
| Cellular Localization | Cytoplasm (By similarity). Membrane (By similarity). Note=Predominantly cytoplasmic (By similarity) Partially membrane-associated (By similarity) |
| Entrez Gene | 50807 |
|---|---|
| Nucleotide Accession | NP_060952.2 |
Application
ASAP1 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ASAP1 antibody detected the ASAP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
