ASAP2 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ASAP2 antibody detected the ASAP2 protein (arrow).
ASAP2; DDEF2; KIAA0400; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Development and differentiation-enhancing factor 2; Paxillin-associated protein with ARF GAP activity 3; Pyk2 C-terminus-associated protein
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
DDEF2 KIAA0400
Alternative Names
ASAP2 DDEF2 KIAA0400 Arf-GAP with SH3 domain ANK repeat and PH domain-containing protein 2 Development and differentiation-enhancing factor 2 Paxillin-associated protein with ARF GAP activity 3 Pyk2 C-terminus-associated protein
Molecular Weight(MW)
111651 Da
Function
Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration
Tissue Specificity
Detected in heart, brain, placenta, kidney, monocytes and pancreas
Cellular Localization
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups
ASAP2 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ASAP2 antibody detected the ASAP2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.