Application
ATAD2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ATAD2 antibody detected the ATAD2 protein (arrow).| Product Name | ATAD2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ATAD2 ATPase family AAA domain-containing protein 2 AAA nuclear coregulator cancer-associated protein |
|---|---|
| Molecular Weight(MW) | 158554 Da |
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells |
| Tissue Specificity | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors |
| Cellular Localization | Nucleus. |
| Entrez Gene | 29028 |
|---|---|
| Nucleotide Accession | NP_054828.2 |
Application
ATAD2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ATAD2 antibody detected the ATAD2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
