ATP13A2 Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ATP13A2 antibody detected the ATP13A2 protein (arrow).
May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity
Tissue Specificity
Expressed in brain; protein levels are markedly increased in brain from subjects with Parkinson disease and subjects with dementia with Lewy bodies. Detected in pyramidal neurons located throughout the cingulate cortex (at protein level). In the substantia nigra, it is found in neuromelanin- positive dopaminergic neurons (at protein level)
Cellular Localization
Membrane; Multi-pass membrane protein (By similarity). Lysosome
ATP13A2 Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ATP13A2 antibody detected the ATP13A2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.