Application
ATP6AP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ATP6AP2 antibody detected the ATP6AP2 protein (arrow).| Product Name | ATP6AP2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ATP6IP2, CAPER, ELDF10 |
|---|---|
| Alternative Names | ATP6AP2 ATP6IP2 CAPER ELDF10 Renin receptor ATPase H(+)-transporting lysosomal accessory protein 2 ATPase H(+)-transporting lysosomal-interacting protein 2 ER-localized type I transmembrane adaptor Embryonic liver differentiation factor 10 N14F R |
| Molecular Weight(MW) | 39008 Da |
| Function | Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) |
| Tissue Specificity | Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta |
| Cellular Localization | Membrane; Single-pass type I membrane protein (Potential) |
| Entrez Gene | 10159 |
|---|---|
| Nucleotide Accession | NP_005756.2 |
Application
ATP6AP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ATP6AP2 antibody detected the ATP6AP2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
