Application
ATRN Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ATRN antibody detected the ATRN protein (arrow).| Product Name | ATRN Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0548, MGCA |
|---|---|
| Alternative Names | ATRN KIAA0548 MGCA Attractin DPPT-L Mahogany homolog |
| Molecular Weight(MW) | 158537 Da |
| Function | Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity) |
| Tissue Specificity | Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted. |
| Entrez Gene | 8455 |
|---|---|
| Nucleotide Accession | NP_647537.1 NP_647538.1 |
Application
ATRN Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ATRN antibody detected the ATRN protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
