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ATPBD3 Antibody (Center)

Catalog Number:OM227254
OM227254
Discount Price
OM227254-100ul
1~2 Week
100ul
OM227254-50ul
50ul
OM227254-20ul
20ul
1~2 Week
Product Profile
Product Name ATPBD3 Antibody (Center)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ATPBD3, NCS6
Alternative Names CTU1
ATPBD3
NCS6
Cytoplasmic tRNA 2-thiolation protein 1
ATP-binding domain-containing protein 3
Cancer-associated gene protein
Cytoplasmic tRNA adenylyltransferase 1
Molecular Weight(MW) 36450 Da
Function Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln) Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position
Tissue Specificity This ATPBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-245 amino acids from the Central region of human ATPBD3.
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 90353
Nucleotide Accession NP_660275.2
Application

Application

ATPBD3 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the ATPBD3 antibody detected the ATPBD3 protein (arrow).

Application

ATPBD3 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATPBD3 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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